达芬奇的恶魔
China approves first-ever drug for acute mountain sickness prevention_我的网站
一 |
过去24小时最大的新闻，莫过于斯洛伐克总理费佐遭遇枪击。
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据Joj电视台报道，菲科被一名来自莱维采的71岁男子开枪击中，凶手已被抓获。
一位不愿透露姓名的女士称她听到三四声枪响，随即看到费佐倒在她面前的地上，他的胸部和头部有血淋淋的伤口。
此后，菲科被直升机送往首都布拉迪斯拉发克拉马雷区的一家医院，并陷入昏迷。
斯洛伐克卫生部长祖扎娜·多林科瓦 (Zuzanna Dolinková) 通报说， “总理仍在接受手术，情况危急， 医生们正在为他的生命而战。”
经调查，刺杀菲科的71岁男子是作家尤拉吉·辛图拉 (Juraj Cintula) ，一位从事中欧调查的记者在社交媒体上发表了一个报告，披露辛图拉背后的秘密（报告很惊人，仅供参考）
据称，此人似乎与亲俄准军事组织斯洛文尼亚分支 (SB) 有关联， 后者的领导人甚至接受过俄罗斯前特种部队士兵的训练。 
China has granted marketing approval of its first drug for the prevention of acute mountain sickness, filling the long-standing gap in the domestic market where no such medications had been available, Science and Technology Daily reported on Tuesday.
The National Medical Products Administration (NMPA) has approved the marketing of acetazolamide sustained-release capsules, the report said. As the first specialized drug in China indicated for preventing of acute mountain sickness, its approval marks the end of the country's lack of dedicated preventive treatment for altitude illness.
By inhibiting the activity of carbonic anhydrase, acetazolamide promotes the renal excretion of bicarbonate, corrects respiratory alkalosis caused by hypoxia at high altitudes, thereby regulating acid-base balance, optimizing respiratory status, elevating blood oxygen levels, and reducing the risk of onset at the source.
In contrast to health products that only provide auxiliary regulatory effects, this medication has been validated through stringent clinical trials and stands as a specialized drug approved by the NMPA with a clear indication for prevention, said the report.
Led by principal investigator is Luobu Gesang, a deputy dean of the People's Hospital of Xizang Autonomous Region, the clinical trial was designed by his team and has yielded critical evidence to inform prevention strategies for altitude sickness that are specifically adapted to Chinese and Asian populations.
"Previously, although acetazolamide had already been used internationally for the prevention of acute mountain sickness, China had long lacked an NMPA-approved acetazolamide formulation supported by rigorous clinical trials. Furthermore, the existing international formulations were short-acting tablets requiring multiple daily doses, and no drugs with the relevant indication were available on the domestic market for an extended period," said Luobu Gesang.
The sustained-release capsule approved this time not only fills this critical gap but also optimizes the dosage form, providing more reliable and convenient medication protection for the physical health and life safety of people entering high-altitude areas, he added.
Clinical trials showed that, compared with the placebo group, the incidence of acute mountain sickness in the medication group was significantly reduced, with the incidence of moderate-to-severe acute mountain sickness decreasing by 14.6 percent, according to the report.
Related research has been published in the international flagship journal of high-altitude medicine, High Altitude Medicine & Biology.
Global Times
。
China has granted marketing approval of its first drug for the prevention of acute mountain sickness, filling the long-standing gap in the domestic market where no such medications had been available, Science and Technology Daily reported on Tuesday.
The National Medical Products Administration (NMPA) has approved the marketing of acetazolamide sustained-release capsules, the report said. As the first specialized drug in China indicated for preventing of acute mountain sickness, its approval marks the end of the country's lack of dedicated preventive treatment for altitude illness.
By inhibiting the activity of carbonic anhydrase, acetazolamide promotes the renal excretion of bicarbonate, corrects respiratory alkalosis caused by hypoxia at high altitudes, thereby regulating acid-base balance, optimizing respiratory status, elevating blood oxygen levels, and reducing the risk of onset at the source.
In contrast to health products that only provide auxiliary regulatory effects, this medication has been validated through stringent clinical trials and stands as a specialized drug approved by the NMPA with a clear indication for prevention, said the report.
Led by principal investigator is Luobu Gesang, a deputy dean of the People's Hospital of Xizang Autonomous Region, the clinical trial was designed by his team and has yielded critical evidence to inform prevention strategies for altitude sickness that are specifically adapted to Chinese and Asian populations.
"Previously, although acetazolamide had already been used internationally for the prevention of acute mountain sickness, China had long lacked an NMPA-approved acetazolamide formulation supported by rigorous clinical trials. Furthermore, the existing international formulations were short-acting tablets requiring multiple daily doses, and no drugs with the relevant indication were available on the domestic market for an extended period," said Luobu Gesang.
The sustained-release capsule approved this time not only fills this critical gap but also optimizes the dosage form, providing more reliable and convenient medication protection for the physical health and life safety of people entering high-altitude areas, he added.
Clinical trials showed that, compared with the placebo group, the incidence of acute mountain sickness in the medication group was significantly reduced, with the incidence of moderate-to-severe acute mountain sickness decreasing by 14.6 percent, according to the report.
Related research has been published in the international flagship journal of high-altitude medicine, High Altitude Medicine & Biology.
Global Times
。
今年1月，“Slovenskí Branci”（SB）的组织庆祝了成立七周年，但它的历史其实相当丰富——它最初是一个未注册的非官方团体，一开始就与另一个极右翼组织——Slovenské Hnutie Obrody密切相关。这个准军事组织一开始就引起了争议，因为它的标志与纳粹青年组织“希特勒青年”非常相似。
该组织成立之后，其领导人什夫切克接受了俄罗斯民兵“民兵组织”的训练，并在俄罗斯逗留了三周。
此外，俄罗斯摩托帮“欧洲夜狼”的头目约瑟夫·汉巴莱克（Jozef Hambálek）是SB的直接支持者，在他的帮助下，SB 成员还在夜狼队斯洛伐克总部接受了涉及装甲运兵车的训练。
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顺便说一下，乌克兰战争期间，SB 前成员凯普塔潜入顿巴斯，加入了亲俄抵抗组织并与他们并肩作战。他目前仍然住在乌克兰东部。
斯洛文尼亚分队的组织和行动与正规军非常相似。
四 | 他们建立了内部等级制度，明确了等级，将成员分为单位或部门，目前数量已达到十七个。
五 | 成员定期招募并接受受斯洛伐克武装部队启发的培训。新兵接受生存、战术、游击战、武器使用、急救、地形甚至基本 CBRN（化学、生物、放射性和核防御）操作方面的训练。
他们招募的主要对象是青少年，通常是军事或类似军事运动的爱好者。
SB鼓励会员穿着军装。
六 | 在演习和仪式等活动中，成员们经常被误认为是正规军人员。直到2019 年，斯洛伐克国防部向国家委员会提交了新法律，禁止穿着此类类似制服。
除了制服外，该组织成员们长期携带气软枪或膨胀枪，这些枪不能射击实弹，但一些SB成员确实拥有真枪并用真枪进行训练，尽管SB在其网站上声称实弹射击演习不是整个组织训练过程的一部分。
据悉，此类演习是由个别部队指挥官组织的，其中一名指挥官兼二把手米哈尔·费林 (Michal Feling) 是斯洛伐克武装部队的成员。
除他之外，SB组织中还有其他斯洛伐克士兵。
2018 年，国防部长彼得·加伊多斯发起一项倡议，禁止现役人员加入斯洛文尼亚分支等组织。
不过，尽管加伊多斯表示现役士兵不能成为斯洛文尼亚分支的成员，但费林仍然是该组织的成员。
七 | 他甚至还受邀参加今年 1 月 5 日的 SB 游行仪式，尽管他没有亲自出席。
此外，加伊多斯还提出过动议，要求检查SB活动的合法性。原因很简单：“类似军事的训练和目标不明确的公民准备，以及可能滥用军事技术”，但这一动议未能获得通过。
总体来看，这个事情非常蹊跷：一位亲俄的总理被一个亲俄的激进组织成员枪杀。一种可能性是他觉认为费科倒的还不够彻底，因为斯洛伐克境内的军工企业照样卖产品给乌克兰，而费科也没有阻挡民间和下面对于乌克兰的支持。
当然，俄罗斯人一定会上“老三部曲”：首先甩锅乌克兰，甩不掉就甩锅美国，还甩不掉，就东拉西扯。
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Published on:09:31:21